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Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate: Moderately clinically significant.
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Real world drug outcomes: Drug interactions of Topamax, Xanax, Zoloft, Remeron, Flector, Voltaren-xr, Vivelle, Protonix, Mobic, Dilaudid, Percocet, Norco, Trazo
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Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate: Moderately clinically significant.
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